Skip to main content

Preventing Deadly Antibiotic Reactions in Children

Two Children’s Mercy doctors on a crusade to address Bactrim-related deaths

 

Zei was Patient Zero.  

 

A healthy high school student, Zei, quickly became dramatically ill and was life-flighted to Children’s Mercy Kansas City. 

A teenage girl with a tube in her nose and in her neck smiles in a hospital bed.
Zei Uwadia

Zei’s lungs were failing and she required the highest level of life support, ECMO, to survive, but every diagnostic test came back “normal.” Doctors were stumped.  

As Zei made national headlines and was hospitalized for 457 days, Dr. Jenna Miller made a startling discovery – before becoming ill, Zei had been prescribed Bactrim for a urinary tract infection.  

In the first ever reported case, Dr. Miller diagnosed Zei with Bactrim-Associated Lung Failure. Sadly, Zei passed away from this deadly drug reaction.

Today, there are 30 confirmed cases of Bactrim-Associated Lung Failure, but we know it is underreported and often underrecognized, which is why we need your help!

Jenna O. Miller, MD, FAAP and Jennifer L. Goldman, MD

Meet the team

 

 

Two women physicians in Kansas City are leading the fight against easily preventable death.

Meet the remarkable team led by Dr. Jenna Miller and Dr. Jen Goldman.

A journey to stop preventable death


Bactrim is an often-prescribed medication for bacterial infections, including as treatment for acne, UTIs and much more. 
 

But it can lead to life-threatening lung failure.  

Children’s Mercy Kansas City is at the forefront of this discovery, the only institution leading Bactrim-Associated Lung Failure diagnosis, treatment and advocacy:

Action plan


World-leading experts at Children’s Mercy Kansas City are hard at work to prevent this life-threatening drug reaction. 
 

With your help, we will:

  • Scale patient identification to help more patients across the country and world. 
  • Enroll and evaluate patients throughout the country. 
  • Manage a research database to further understand this deadly reaction. 
  • Perform world-leading genomic analysis to diagnosis more children before it’s too late.  
  • Create treatment protocols for hospitals around the country and world to use treating this reaction.  
  • Provide a genomic test prior to prescribing Bactrim to ensure all children with a genetic-predisposition to a life-threatening drug response don’t receive the medication.

Donate


Join us to save lives. 
 

Together, we’ll advance disease discovery and treatment to diagnose more children before it’s too late.

Submit your case


Do you suspect your loved one or someone you know might have Bactrim-Associated Lung Failure? We know this is a very underreported and often underrecognized disease, so please reach out!

Submit their case to add to our body of research providing hope to future families.

How you can help

Donate


Join us to save lives. 
 

Together, we’ll advance disease discovery and treatment to diagnose more children before it’s too late.

Submit your case


Do you suspect your loved one or someone you know might have Bactrim-Associated Lung Failure? We know this is a very underreported and often underrecognized disease, so please reach out!

Submit their case to add to our body of research providing hope to future families.

Spread the word


Too few families and physicians know of, or understand, Bactrim-Associated Lung Failure. 
 

Send this website to others to help spread the word and save lives.

childrensmercy.org/bactrim