Bradley A. Warady, MD
McLaughlin Family Endowed Chair in Nephrology; Division Director, Pediatric Nephrology; Director, Dialysis & Transplantation; Professor of Pediatrics, University of Missouri-Kansas City School of Medicine; Education Professor of Pediatrics, University of Kansas School of Medicine
Full BiographyBradley Warady, MD, Director, Division of Nephrology, received a five-year, $5,795,168 U01 award from the National Institute of Diabetes and Digestive and Kidney Diseases - National Institutes of Health (NIDDK/NIH) for the project, “Chronic Kidney Disease in Children (CKiD V).”
Children with chronic kidney disease (CKD) face increased health risks beyond their primary kidney disorder. Those risks include cardiovascular disease, metabolic bone disease and high mortality rate in young adulthood. Children with CKD also face challenges with social and emotional well-being.
CKiD V continues the observational CKiD study that began in 2003 and that follows 1,100 children with mild to moderate chronic kidney disease. The study has more than 50 participating pediatric nephrology centers across the United States and Canada. The study’s long-term goals include:
- Enhance the current cohort to collect additional data as the new and existing cohorts become young adults.
- Define how risk factors for glomerular filtration rate (GFR) decline and how early cardiovascular abnormalities detected during childhood impact long-term health outcomes after transition to adulthood.
- Examine the impact of risks developed during childhood CKD on outcomes in adulthood by linking CKiD data with external national databases.
- Assess the social functioning and emotional well-being of children with CKD to understand their impact on subsequent clinical care and life course.
“We are so grateful to receive funding from the NIH to continue the work that began 20 years ago and that has yielded findings that have positively impacted the care of children with CKD around the globe,” Dr. Warady said. “While we never imagined being funded this long at the time of our initial award, we have been very productive as a result of the efforts of so many, and we are excited about the prospect of generating new and meaningful data over the next five years.”
The contents are those of the investigator and do not necessarily represent the official views of, nor an endorsement, by NIH, or the U.S. Government.