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Functional Impairments: A study collecting data for researchers to find better treatments for children and adults who take specific medications.

This study is being done on child/adults: • 1 - 26 Years old • Patients that have schedule procedures that will involve the collection of CSF and blood Centrally Acting Molecules Study is a database that will collect information about how certain medications cross the blood-brain barrier in patients who have functional, spinal and or brain impairments. This research study is done to see how much medication crosses a barrier to get into fluid surrounding the brain and spinal cord. This research study involves collecting blood, left over cerebrospinal fluid(CSF) samples and data from standard care services that are a part of the care that the patient will already receive, including a lumbar puncture or surgery.

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Full Study Name: Centrally Acting Molecules Study

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