About the Study

B-Cell Non-Hodgkin Lymphoma (B-NHL): A study of glofitumab with or without chemotherapy in children with relapsed or refractory mature B-NHL

This study is for: • Part 1: Patients who are greater than 6 months old to less than 18 years old • Part 2: Patients who are greater than 6 months old to less than 31 years old • Who have been diagnosed with mature B-Cell non-Hodgkin lymphoma that has relapsed (has come back) or is refractory (has not responded to earlier treatment) The goal of this study are to find what effects, good and/or bad, the drug glofitumab with or without chemotherapy has on children and young adults with relapsed or refractory mature B-NHL. Part 1 is looking learn more about the pharmacology (for example, the best dose) of the medication. Part 2 increases the number of participants based on what is learned from Part 1.

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Full Study Name: CO43810