About the Study

Severe respiratory illness: Exposure to an antibiotic called Bactrim

This study is for children: 1. 3-18 years old 2. Who had greater than or equal to 6 days of exposure to treatment doses of Bactrim 3. Who developed severe respiratory failure leading to an ICU admission with need for a ventilator and/or ECMO The goal of this study is to further define the lung failure process the follows that can rarely follow Bactrim exposure. There are several well understood adverse reactions to Bactrim but severe lung failure is only recently recognized and reported. Researchers need to evaluate more patients to understand why this rare reaction happens to some children and not others.

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Full Study Name: Severe respiratory illness in children exposed to trimethoprim-sulfamethoxazole (TMP-SMX)