Antibiotics
References
Children’s Hospital Association Improving Pediatric Sepsis Outcomes (IPSO) Collaborative Infectious Disease Workgroup and Antimicrobial Recommendations Working Group. (2018). Improving pediatric sepsis outcomes (IPSO): Recommendations for empiric antimicrobial treatment by site of suspected/identified infection. Children’s Hospital Association.
Tang Girdwood, S., Dong, M., Tang, Pl, Stoneman, E., Jones, R., Yunger, T., Ostermeier, A., Curry, C., Forton, M., Hail, T., Mullaney, R., Lahni, P., Punt, N., Kaplan, J., & Vinks, A.A. (2022). Population pharmacokinetic modeling of total and free ceftriaxone in critically ill children and young adults and Monte Carlo simulations support twice daily dosing for target attainment. Antimicrobial Agents and Chemotherapy, 66 (1), e0142721. https://doi.org/10.1128/AAC.01427-21
These pathways do not establish a standard of care to be followed in every case. It is recognized that each case is different, and those individuals involved in providing health care are expected to use their judgment in determining what is in the best interests of the patient based on the circumstances existing at the time. It is impossible to anticipate all possible situations that may exist and to prepare a pathway for each. Accordingly, these pathways should guide care with the understanding that departures from them may be required at times.