Research Studies and Clinical Trials Search
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Anxiety and Depression: A study of how the body breaks down medicine
This study involves: - Children and teens age 6-18 - Taking the prescribed medicine every day for 2 weeks without missing any doses - A one-time 24-hour visit in the Pediatric Clinical Research Unit...
This study involves: - Children and teens age 6-18 - Taking the prescribed medicine every day for 2 weeks without missing any doses - A one-time 24-hour visit in the Pediatric Clinical Research Unit Researchers at Children's Mercy are doing this study to learn more about how the body breaks down medicine for depression and/or anxiety. Children and teens who are prescribed fluoxetine (Prozac®), sertraline (Zoloft®), or escitalopram (Lexapro®) are eligible to participate
Brain Response to Medicines: A study to learn how the brain of a person with ADHD or depression responds to medicine
This study is being done for: -Children and adults ages 7 to 25 years old -Children and adults with ADHD previously enrolled in the ATX PBPK-PD-Clinical Outcomes Study at Children's Mercy -Children and adults with depression who previously participated in the GOLDILOKs PRISM...
This study is being done for: -Children and adults ages 7 to 25 years old -Children and adults with ADHD previously enrolled in the ATX PBPK-PD-Clinical Outcomes Study at Children's Mercy -Children and adults with depression who previously participated in the GOLDILOKs PRISM Study at Children's Mercy The goal of the study is to learn more about how exactly brain cells respond to ADHD and/or depression medicines and learn if researchers can predict whether a child or adult's ADHD or depression symptoms will improve with these certain medicines.
Depression: A study of fluoxetine (Prozac®) and escitalopram (Lexapro®) in teens and adolescents
This study is for teens: • Ages (12-18) • With depression diagnosis The goal of this study is to understand why the antidepressant medicines fluoxetine (Prozac®) and escitalopram...
This study is for teens: • Ages (12-18) • With depression diagnosis The goal of this study is to understand why the antidepressant medicines fluoxetine (Prozac®) and escitalopram (Lexapro®) work for some teens with depression and not for others. Every teen and their depression are unique, and there is no one-size fits all treatment. What researchers learn from this study could help the care team find the right treatment sooner, which could lead teens on a quicker path to recovery.
Improve treatment: Understanding the amount of fluoxetine, escitalopram, pimozide, pantoprazole, and lansoprazole that reaches the brain in teens and young adults
This study is being done for teens and young adults: • Ages 12 to 21 • Currently taking or recently stopped taking fluoxetine, escitalopram, pimozide, pantoprazole, or lansoprazole • Able to have a special brain scan (MRI), a blood draw, and answer brief questionnaires...
This study is being done for teens and young adults: • Ages 12 to 21 • Currently taking or recently stopped taking fluoxetine, escitalopram, pimozide, pantoprazole, or lansoprazole • Able to have a special brain scan (MRI), a blood draw, and answer brief questionnaires The goal of this study is to measure the amount of certain medications in the brain.
Type 1 Diabetes: Reduce feelings of diabetes distress
This study is for children: • Ages 8-12.99 • Who have Type 1 Diabetes • Are on intensive insulin treatment...
This study is for children: • Ages 8-12.99 • Who have Type 1 Diabetes • Are on intensive insulin treatment • English is their primary language The purpose of this research study is to test whether a treatment program works to help families of school-age children with T1D reduce any feelings of diabetes distress and improve glucose levels. Families participate via a computer, tablet, or smartphone. Families will also upload continuous glucose monitoring (CGM) data.