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Hemophilia: A study investigating inflammation and iron homeostasis
The primary objective of this study is to determine if there is an association of factor 8 or 9 activity with inflammatory markers, hepcidin, and iron stores in children and young adults with hemophilia A and B. Inclusion Criteria...
The primary objective of this study is to determine if there is an association of factor 8 or 9 activity with inflammatory markers, hepcidin, and iron stores in children and young adults with hemophilia A and B. Inclusion Criteria: • Less than 22 years of age • Able to comprehend English and/or Spanish • Participants must be diagnosed with Hemophilia A (Factor 8 deficiency) or Hemophilia B (Factor 9 deficiency) Being in this study will involve one study visit which will last approximately 20-30 minutes. The study visit can happen at the same time as the child regular clinic visit. The biggest risks from being in this study are bleeding and discomfort related to the blood draw. There may be direct benefit to being in this study: any iron deficiency discovered from study labs can be treated by the primary hematologist. By being in this study, children may help researchers find better treatments for patients with hemophilia in the future.