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Statin: A study to understand how liver fat affects liver cell processes
This study is for children: • 8-21 years • LDL cholesterol >130mg/dl (>95% percentile) • Fasting overnight (~8 hrs.)...
This study is for children: • 8-21 years • LDL cholesterol >130mg/dl (>95% percentile) • Fasting overnight (~8 hrs.) The purpose of this research study is to determine the role that liver fat has on movement of drug into the liver and how liver fat affects the response to a drug used to lower cholesterol (statin). A goal of the study is to determine if increased liver fat leads to less movement of a drug into the liver and less response to statins, potentially placing a patient with higher liver fat at risk for side effects and treatment failure.