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Provider resources for antimicrobial stewardship

A pediatric guide from Children's Mercy Kansas City

The following resources may be helpful in staying up to date on current best practices in antimicrobial stewardship.
 

Pediatric Outpatient Antibiotic Handbook


The Children’s Mercy Antimicrobial Stewardship Program (ASP) developed the Outpatient Antibiotic Handbook as guidance for providers who treat common pediatric infections, such as Acute Otitis Media, Group A Streptococcal Pharyngitis, Community Acquired Pneumonia, Sinusitis, UTI, Skin and Soft Tissue Infections, Animal/Human Bites, Lymphadenitis, Bacterial Conjunctivitis, and Dental Abscesses. The handbook contains diagnostic pearls as well as guidance on antibiotic selection, allergy alternatives, dosing and duration of treatment. 

Access the Outpatient Antibiotic Handbook
 

“Stewie Shares” infographics 


Each month, our ASP team publishes an educational infographic entitled “Stewie Shares.” These provide brief, organized education targeted at both the clinician and non-clinician.

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“Wise Use of Antibiotics” column in The Link


Articles written by our ASP team on various antimicrobial stewardship practices are published in the monthly digital newsletter, The Link, which is available for all pediatric providersSubscribe to receive The Link directly to your email each month.

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Featured Publications  


Development and Implementation of the Antimicrobial Stewardship Intervention Scoring Tool at a Single Pediatric Institution 

A key component of ASPs has been ongoing monitoring of various metrics; however, recommended metrics do not adequately depict the direct impact of the ASP on patient safety, which is an important metric for both hospital leadership who are charged with resource allocation and frontline teams who are responsible for implementing change. There is a need for an objective, quantifiable measure to assess antimicrobial-associated patient harm avoided due to ASP intervention. In this publication, our ASP describes the development of a novel metric—the Antimicrobial Stewardship Impact Scoring Tool (ASIST)—which associates each inpatient ASP prospective audit and feedback (PAF) intervention with a level (high, moderate, low impact) of patient harm prevention and antimicrobial optimization.

Wirtz AL, Burns AN, Monsees EA, Lee BR, Herigon JC. Development and implementation of the antimicrobial intervention scoring tool (ASIST) at a single pediatric institution. Infect Control Hosp Epidemiol. 2024;16:1-6. PMID: 39279733. 

Sociodemographic Differences in Treatment of Acute Respiratory Infections in Pediatric Urgent Cares 

Reports from primary care clinics, urgent care clinics, and emergency departments show high rates of antibiotic use and non-first-line antibiotic use in White non-Hispanic children compared to other races and ethnicities. Differences in management of patients with common infections have been shown to persist across race, ethnicity, insurance status, and language. These differences in antibiotic use suggest that health inequities may exist. In this publication, our ASP utilizes data obtained from 9 institutions participating in a Children's Mercy-led multicenter collaborative (REDUCE) to determine whether differences exist in antibiotic prescribing for respiratory infections in pediatric urgent care centers by patient race/ethnicity, insurance, and language.

El Feghaly RE, Sainz LE, Lee BR, Kronman MP, Hersh AL, Parente V, Bizune D, Sanchez GV, Hamdy RF, Nedved A; For REDUCE (Reducing Differences in Urgent Care Encounters – Antibiotic Choice) Collaborative. Sociodemographic differences in treatment of acute respiratory infections in pediatric urgent cares. Infect Control Hosp Epidemiol. 2024 Dec 3:1-9. doi: 10.1017/ice.2024.196. Epub ahead of print. PMID: 39623533.

At the Break Point: What Needs to Change for Antimicrobial Stewardship Program Pharmacists? 

The dual threats of antimicrobial resistance and antimicrobial-related patient harm are only increasing. Antimicrobial stewardship is needed now more than ever. Strong, well-trained, experienced ASP pharmacists are critical for successful stewardship and protecting our patients. However, many ASP pharmacists "burn out by the time they are in their mid-30s." In this publication, members of the Children's Mercy ASP partner with ASP team members from external institutions to list modifiable contributors to burnout for ASP pharmacists and provide action steps for health systems, pharmacy departments, and ASP leadership to promote change.

Wirtz AL, Metjian TA, Parker SK, Herigon J, MacBrayne CE. At the break point: What needs to change for antimicrobial stewardship program pharmacists? Am J Health Syst Pharm. 2024;81(24):1322-1326.


The Critical Role of Nurses in Antibiotic Stewardship

The Centers for Disease Control and Prevention (CDC) and American Nurses Association (ANA) identify staff nurses as critical players in the antibiotic stewardship movement. Nurses practice across the care continuum, often in settings where infectious diseases experts are lacking. As the largest discipline in healthcare, with significant influence on care, nurses are uniquely positioned to support stewardship strategies by assessing for an accurate allergy history, obtaining necessary cultures before antibiotics are administered, assessing for adverse events, managing clinical progress through outpatient management, and providing education to ensure antibiotic adherence.

Integrating bedside nurses into antibiotic stewardship: A practical approach

Monsees EA, Tamma PD, Cosgrove SE, Miller MA, Fabre V. Integrating bedside nurses into antibiotic stewardship: A practical approach. Infect Control Hosp Epidemiol. 2019 May;40(5):579-584. doi: 10.1017/ice.2018.362. Epub 2019 Feb 21. PMID: 30786944.

Implementation of a nurse-driven antibiotic engagement tool in 3 hospitals 

Monsees E, Lee B, Wirtz A, Goldman J. Implementation of a nurse-driven antibiotic engagement tool in 3 hospitals. Am J Infect Control. 2020 Dec;48(12):1415-1421. doi: 10.1016/j.ajic.2020.07.002. Epub 2020 Jul 6. PMID: 32645472.

References 

  1. Fleming-Dutra KE, Hersh AL, Shapiro DJ, et al. Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011. JAMA 2016;315:1864-73. 
  1. Poole NM, Shapiro DJ, Fleming-Dutra KE, Hicks LA, Hersh AL, Kronman MP. Antibiotic Prescribing for Children in United States Emergency Departments: 2009-2014. Pediatrics 2019;143.