Research Studies and Clinical Trials Search
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Eating Disorders: A study to understand brain response to Naltrexone in teens and young adults
Children's Mercy (Research Institute/Division of Adolescent Medicine and Clinical Pharmacology) is doing a research study to understand brain differences in the reward system of teens and young adults with eating disorders. The study involves a one-time dose of a medication...
Children's Mercy (Research Institute/Division of Adolescent Medicine and Clinical Pharmacology) is doing a research study to understand brain differences in the reward system of teens and young adults with eating disorders. The study involves a one-time dose of a medication called naltrexone. Naltrexone is used in many conditions in adults and children from autism to eating disorders. It is most known for preventing drug abuse in adults. In patients with eating disorders, it is used to reduce binge eating and purging (such as vomiting). The study team previous work showed that naltrexone helps some patients with eating disorders, but not all. The study team wants to understand why some patients respond and others don't.
Prader-Willi Syndrome: A study of a nasal spray called Carbetocin and its potential to slow down hunger
This study is for people: • Who are ages 5-21 • With Willi syndrome (PWS) diagnosis...
This study is for people: • Who are ages 5-21 • With Willi syndrome (PWS) diagnosis The purpose of this research study is to investigate the efficacy and safety of carbetocin nasal spray for a symptom of PWS called hyperphagia, or increased appetite. Carbetocin is related to a hormone called oxytocin, which is involved in regulating hunger, bodyweight, and energy use. Low levels of oxytocin in the brain have been found in PWS. Carbetocin may help reduce the hyperphagia caused by PWS.